I have one of those regulated valves and I use it on a buddy bottle dedicated to filling my target pistol. Honestly, I would not want it on my main tanks as I would not want to keep resetting it for different guns, especially my Huben that can take more pressure than I can feed it anyways.
I think it would be fine on a bottle dedicated to regulated use with minimal different settings - preferably none like I do with mine. Otherwise, I thin an inline regulator is a better option - especially if you have only one main tank and multiple guns.
It would be nice to have a regulator that allows for changes on the fly, but I am good with the set up I have with the Karakusher regulator for most tethering sessions, as it saved me so much money.