@ 25 yards the .25 cal will have about 43 FPE of retained energy and about 7.7" wound depth.
@ 25 yards the .3 cal will have about 36 FPE of retained energy and a 5.6" wound depth
This is according to pyramidair's bullet effectiveness calculation, and retained energy calculation.
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I don't see how a 40 fpe .30 cal here wins against a 49 fpe .25 cal, one should simply test this empirically with some penetrative testing on similar targets to what OP is aiming to shoot.
-Matt