If you needed to take out a raccoon . . .

As many have mentioned a headshot is the most lethal, I had to dispatch a raccoon on my property that was in my horses pasture couldnt use a rimfire rifle so I grabbed the next best thing. Which was my Crosman .177 Nitro Piston, he was about 20ft up a tree and I was about 5-8 yards away from the base if said tree to get a better angle for my trajectory one shot to the back of the head done him in. 
 
Another reason to eliminate them is Leptospirosis. There were several pets on the block that contracted the disease, I was fortunate as my chihuahua was the only one to survive it.. I had a live and let live attitude up till then. A 20 ft.lb 22 cal is more than adequate for sub 20 yard shots, with the best results shooting at the base of the skull getting spine - brain. They're breeding machines, it's not uncommon to see a mother with here full brood openly walking the streets during daylight hours in my neighborhood.