Yes, drying on the output (i.e. high pressure) side is much more effective than drying on the input. Cool air, and high pressure air, can hold less moisture than warm, and low pressure air. Warm air can keep more water vapor molecules suspended, because the air molecules themselves are bouncing around more than when cool. High pressure/compressed air has less space available between the air molecules to hold water vapor molecules.
Time is another factor. The longer air containing water vapor molecules can remain in contact with desiccant, the more moisture can be removed.
Having said that, you do have to pay more attention when drying on the output, as fittings & containers need to be rated at more than the expected pressure level (for safety). Fittings & containers on the input side can be about anything.
Many do find that using desiccant on the input makes a noticeable difference, and as @douger said above, any filtering is better than none. However, for most users, atmospheric pressure air compressed to upwards of 4500psi/310 bar is going to be fully saturated, no matter how dry it was to start with, simply because it's being squeezed into 1/310th the space (standard atmospheric pressure is 14.7psi or about 1 bar). So, while that high pressure air can't hold as much moisture as lower pressure air, it's also hot due to being compressed, so that increases its moisture capacity.
So, compress your air (use desiccant on the intake if you want), then cool it quickly & let it spend a little time traveling through desiccant on its way out. Add a large coalescing filter before the output desiccant if you're in a more humid environment. They don't have a filtering medium to replace, so that helps offset their higher cost, plus they'll help your desiccant last longer.
Some good threads on this topic:
https://www.gatewaytoairguns.org/GTA/index.php?topic=139845.msg1407834#msg1407834, and
https://www.gatewaytoairguns.org/GTA/index.php?topic=140456.msg1416031#msg1416031.
That Air Venturi filter in the original post is a serious rip-off. 1) Being open to the atmosphere, it won't take long to saturate, 2) silica gel is more effective than molecular sieve at moderate & higher humidity levels (i.e. what you have in your house), and 3) it isn't built well enough to repurpose it for use on the high pressure output.