Tuning Is Thread Sealer necessary on...

O-rings should have light coat of 100% silicone grease so they seat & don't get cut. 
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I'm replacing the external regulator and would like to know if any sealer is necessary for the threads to the bottle and to the gun and if so, what type of sealer?

Thank you for taking the time to respond.


I think OP meant internal reg. 

This is an external regulator for shooting while tethered & having full control and fast adjustments of pressure. Not just for air hog airguns.
Helps to find out what pressure works best harmonically, valve timing, etc. much easier than a internal reg that must be set up with tester and put back in airgun every time. 

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