I don't understand why FX won't just make a faster twist liner for the .177 slug guns. They are crazy fun and capable. I think they should offer a 16" twist minimum, but a twist as low as 12-14" twist would be optimal. As qball mentioned, it is hard to push heavy 20+ grain .177 slugs at proper speeds, and a lot of people don't understand how hard that really is. You just about have to tune your reg settings like you trying to shoot 40 grain 22 slugs, lol. The difference is less hammer is required.
My results with the 370mm twist Afla Precision barrel have been awesome, but that requires machining a barrel to fit the gun, and they are hard to come by here. Going by the twist calculators they should be marginal with accuracy, but they are LASERS out of that barrel. I never have fliers and I trust that barrel slug combo more than any other caliber I shoot for out of the case accuracy. They just shoot like clockwork every single time. Just goes to show the twist calculators aren't cut and dry, but rather a good place to start in many cases. The real truth is unveiled when we can put some lead on target.
I have tested 22/23 grain .177 slugs out to 325 yards with that setup, and they perform quite well. I estimate the BC to be around .11-.12 at the speeds I'm shooting(1050-1070fps), but they do hold up very well. I don't think they'll be dethroning the .22 either, but man are they fun! Those little ice picks get to target fast! You won't really see a bump in shot count over .22 with a HIGH power .177 setup, but they are quieter and useful for more than just targets.