You really can't manhandle an FX like you would a normal rifle. They're great shooters but the second you put pressure on that barrel, you need to rezero. Thats the downside of being able to remove a barrel in 30 seconds.
If I take my Dreamline out for hunting or pest control I immediately zero my gun when I get there. I carry a sleeve of one inch stickers in my truck for basically that exact purpose. It's never out a whole lot but an inch at 50yds is enough to be problematic when trying to pop a squirrel or rabbit in the dome.