"prfssrlee"Mike's explanation is nice and intuitive I think. Water doesn't compress, air does. We all agree that drying on the high pressure side is way more efficient than drying on the inlet side alone. But look at the psychro chart... if you start with 20% RH air at 25C, your inlet air has about 4 grams of water per kilogram of dry air, but if your inlet air is at 80% RH at 25C then you have about 16 grams of water per kilgram of dry air. That is 4 times more water that will need to be removed on the high pressure side, hence my comment earlier about drying the inlet to extend the time between dessicant changes on the high pressure side. Drying on both ends is certainly better than drying on just the high side (but only if you can dry the low pressure side effectively - just sticking some dessicant on the inlet at 1 atmosphere of pressure won't do anything meaningful). If you have to choose to do one thing, then put your dryer on the high pressure side.
I'm going to try running the YH as a booster this weekend with 45 psi air on the inlet - lots of reasons why I think that might work well, but certainly increasing the efficiency of air drying is one of them (as is prolonging motor life, shorter fill times or ability to fill larger tanks, ability to run the YH longer and at lower temps since it doesn't have to work as hard to go from 450psi to 4500 psi, etc). Hopefully the first stage outlet can handle 450psi since it runs a 10:1 compression ratio.