I shoot out to 400 yards and this is how I do it with only two turret adjustments:
Buy an Athlon Argos, Midas Tac, or Ares with any of the three Christmas tree reticles: APLR2, APLR3, APLR4. All of these reticles have 40 MOA of vertical and range in price from $400-$850. Use no-limit rings so you can adjust an approximate 50 yd zero with your scope turret close to zero MOA so you don't waste any scope adjustment. What muzzle velocity and slug you are using will determine how many MOA you need out to 400 yd s. My muzzle velocity is 1075 fps and with the slugs I am using I need 84 MOA to get out to 400 yds. 40 MOA on the reticle gets me out to 250 yards. Then I make one turret change of +40 MOA which essentially resets my reticle back to zero. Then I use the reticle again to shoot from 275 yards to 375 yards. I do a second turret increase of +40 MOA (80MOA total) which essentially resets the reticle a second time to zero. I then can get my final 400 yard distance at 84 MOA (at this point 4 MOA on the reticle). I sight-in all my yardages in 25 yd increments from 50 to 400 yards.