I mean, PRS rimfire is .22 cal. With the advancements in airguns and ammo happening, you can't expect them to remain more or less unregulated forever. Even rimfire has restrictions, such as standard velocity ammo only, nothing supersonic. I would not be surprised to see more restrictions on airguns in the coming years. A 49 gr .25 cal Altaros slug with a G1 BC over .21 is practically unfair to 22LR already. The best rimfire G1 BC out there now is for Lapua at about .172. I shoot the Altaros .22 cal Kings, and I have a noticeable advantage in the wind.
If manufacturers want to make airguns more competitive, build better chassis and air systems.